Ihe omumu ohuru akpọrọ “Iji Pix-2-Pix GAN maka Ọmụmụ Ihe Dị omimi dabere na Ahụ PSMA PET/CT Attenuation Correction” ka ebipụtara n'oge na-adịbeghị anya na Mpịakọta 15 nke Oncotarget na Mee 7, 2024.
Mkpughe radieshon sitere na usoro ọmụmụ PET/CT na nsonye onye ọrịa oncology bụ nchegbu. Na nyocha a na-adịbeghị anya, otu ndị nchọpụta gụnyere Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey, na Stephanie A. Harmon sitere na National Cancer Institute na National Institutes of Health webatara ngwá ọrụ ọgụgụ isi (AI). Ngwá ọrụ a na-achọ ịmepụta ihe oyiyi PET (AC-PET) nke attenuation deziri site na ihe oyiyi PET (NAC-PET) na-adịghị emezigharị, nwere ike ibelata mkpa maka nyocha CT dị ala.
"Onyonyo PET nke Ai mepụtara nwere ikike ụlọ ọgwụ iji belata mkpa maka mgbazi attenuation na nyocha CT ma na-echekwa akara ọnụọgụ na ogo onyonyo maka ndị ọrịa prostate."
Ụzọ: Algọridim mmụta miri emi dabere na ụlọ ọrụ 2D Pix-2-Pix generative adversarial network (GAN) ka emepụtara dabere na ihe oyiyi AC-PET na NAC-PET jikọtara ọnụ. E kewara 18F-DCFPyL PSMA (Prostate-specific membrane antigen) PET-CT ọmụmụ nke ndị ọrịa 302 nwere ọrịa kansa prostate n'ime ọzụzụ, nkwado, na otu nnwale (n 183, 60, na 59, n'otu n'otu). A zụrụ ihe nlereanya a site na iji atụmatụ abụọ ahaziri ahazi: Standard Uptake Value (SUV) dabere na SUV-NYUL dabere. A tụlere nyocha arụmọrụ kwụ ọtọ site na iji njehie pụtara square (NMSE), pụtara njehie zuru oke (MAE), nhazi myirịta (SSIM) na oke mgbama na mkpọtụ (PSNR). Dọkịta na-ahụ maka ọgwụ nuklia mere nyocha ọkwa ọnya nke mpaghara mmasị. A tụlere ihe ngosi SUV site na iji ọnụọgụ mmekọrịta nke intra-group (ICC), ọnụọgụ ugboro ugboro (RC), na ụdị mmetụta agwakọta nke ahịrị.
Nsonaazụ:N'ime otu nnwale nọọrọ onwe ya, etiti NMSE, MAE, SSIM, na PSNR bụ 13.26%, 3.59%, 0.891, na 26.82, n'otu n'otu. ICC maka SUVmax na SUVmean bụ 0.88 na 0.89, na-egosi njikọ siri ike n'etiti ihe nrịbama ihe onyonyo izizi na AI mepụtara. Achọpụtara ihe ndị dị ka ebe mmerụ ahụ, njupụta (nkeji Hounsfield), na ọnya ọnya na-emetụta njehie ikwu na metric SUV emepụtara (niile p <0.05).
“AC-PET nke ụdị Pix-2-Pix GAN mepụtara na-egosipụta metrik SUV nke dabara na onyonyo izizi. Onyonyo PET nke AI mepụtara na-egosipụta ikike ụlọ ọgwụ na-ekwe nkwa ibelata mkpa nyocha CT maka mgbazi attenuation ka ị na-ejigide akara ọnụọgụ na ogo onyonyo.
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Dị ka anyị niile maara, mmepe nke ụlọ ọrụ na-ahụ maka ahụike na-enweghị atụ na mmepụta nke usoro ngwá ọrụ ahụike - ndị na-emepụta ihe dị iche iche na ihe ndị na-akwado ha - nke a na-ejikarị eme ihe na mpaghara a. Na China, nke a ma ama maka ụlọ ọrụ mmepụta ihe, e nwere ọtụtụ ndị na-emepụta ihe a ma ama n'ụlọ na ná mba ọzọ maka mmepụta ihe ngosi ahụike, gụnyere.LnkMed. Kemgbe e guzobere ya, LnkMed anọwo na-elekwasị anya n'ọhịa nke injectors iche iche dị elu. Ndị otu injinia LnkMed bụ ndị Ph.D na-edu. nwere ihe karịrị afọ iri nke ahụmahụ ma na-etinye aka na nyocha na mmepe. N'okpuru nduzi ya, ndịCT injector otu isi,CT injector isi okpukpu abụọ,MRI iche ihe injector, naAngiography elu-nrụgide dị iche iche ihe injectorA na-eji atụmatụ ndị a eme ya: ahụ siri ike na kọmpat, interface dị mfe na nke nwere ọgụgụ isi, ọrụ zuru oke, nchekwa dị elu, na imewe na-adịgide adịgide. Anyị nwekwara ike ịnye syringes na tube nke dabara na ụdị ndị a ma ama nke CT, MRI, DSA injectors Site n'ezi omume ha na ike ọkachamara, ndị ọrụ niile nke LnkMed ji ezi obi na-akpọ gị òkù ka ị bịa nyochaa ahịa ọnụ.
Oge nzipu: Mee-14-2024
